VN May 2024

VET Mei / May 2024 The Monthly Magazine of the SOUTH AFRICAN VETERINARY ASSOCIATION Die Maandblad van die SUID-AFRIKAANSE VETERINÊRE VERENIGING Ionophore Toxicity in Cattle CPD THEME WVAC 2024 nuus•news CPD article QR code

Dagboek • Diary Ongoing / Online 2024 May 2024 August 2024 SAVETCON: Webinars Info: Corné Engelbrecht, SAVETCON, 071 587 2950, corne@savetcon.co.za / https://app.livestorm.co/svtsos Acupuncture – Certified Mixed Species Course Info: Chi University: https://chiu.edu/courses/cva#aboutsouthafrica@tcvm.com SAVA Johannesburg Branch CPD Events Monthly - please visit the website for more info. Venue: Johannesburg Country Club Info: Vetlink - https://savaevents.co.za/ Online CPD Course: Animal doctor’s guide to managing humans! 05-25 May Venue: ONLINE Info: www.vetskillsts.co.za SAVA Mpumalanga Branch CPD evening 16 May: Venue: Protea Hotel Nelspruit Info: conference@savetcon.co.za SAVA Oranje Vaal Branch CPD day 18 May: Venue: Willow Banks Lodge, Parys Info: conference@savetcon.co.za or https://savetcon. co.za/2024-world-veterinary-association-congress-2/ SAVA Western Cape Branch Congress 02-03 August Venue: Protea Hotel, Technopark, Stellenbosch Info: www.vetlink.co.za SAVA Oranje Vaal Branch Mini Congress 09-11 August Venue: Parys – venue to be confirmed. Info: conference@savetcon.co.za September 2024 October 2024 NVCG Bush Break 12-13 August Venue: Skukuza, Kruger National Park Info: https://vetlink.co.za/nvcg-2024/ 8th World One Health Congress 20-23 September Venue: CTICC, Cape Town, South Africa Info: https://globalohc.org/8WOHC or contact conferences@vetlink.co.za SAVA Northern Natal and Midlands Branch Congress 05-06 October Venue: Lythwood Lodge, Midlands Info: www.vetlink.co.za PARSA Conference 06 – 08 October Venue to be confirmed: Gauteng Info: corne@savetcon.co.za SAAVT 2024 Conference 09 – 10 October Venue: 26 Degrees South, Muldersdrift conference@savetcon.co.za or https://savetcon.co.za/2024-saavt-biennial-congress/ 12th IAVRPT Symposium 2024 30 October – 02 November Venue: Somerset-West, Cape Town, South Africa Info: https://iavrpt2024.co.za/ or contact conferences@vetlink.co.za

Vetnuus | May 2024 1 Contents I Inhoud President: Dr Paul van der Merwe president@sava.co.za Managing Director: Mr Gert Steyn md@sava.co.za/ +27 (0)12 346 1150 Editor VetNews: Ms Andriette van der Merwe vetnews@sava.co.za Bookkeeper: Ms Susan Heine accounts@sava.co.za/+27 (0)12 346 1150 Bookkeeper's Assistant: Ms Sonja Ludik bookkeeper@sava.co.za/+27 (0)12 346 1150 Secretary: Ms Elize Nicholas elize@sava.co.za/ +27 (0)12 346 1150 Reception: Ms Hanlie Swart reception@sava.co.za/ +27 (0)12 346 1150 Marketing & Communications: Ms Sonja van Rooyen marketing@sava.co.za/ +27 (0)12 346 1150 Membership Enquiries: Ms Debbie Breeze debbie@sava.co.za/ +27 (0)12 346 1150 Vaccination booklets: Ms Debbie Breeze debbie@sava.co.za/ +27 (0)12 346 1150 South African Veterinary Foundation: Ms Debbie Breeze savf@sava.co.za/ +27 (0)12 346 1150 Community Veterinary Clinics: Ms Claudia Cloete cvcmanager@sava.co.za/ +27 (0)63 110 7559 SAVETCON: Ms Corné Engelbrecht corne@savetcon.co.za/ +27 (0)71 587 2950 VetNuus is ‘n vertroulike publikasie van die SAVV en mag nie sonder spesifieke geskrewe toestemming vooraf in die openbaar aangehaal word nie. Die tydskrif word aan lede verskaf met die verstandhouding dat nóg die redaksie, nóg die SAVV of sy ampsdraers enige regsaanspreeklikheid aanvaar ten opsigte van enige stelling, feit, advertensie of aanbeveling in hierdie tydskrif vervat. VetNews is a confidential publication for the members of the SAVA and may not be quoted in public or otherwise without prior specific written permission to do so. This magazine is sent to members with the understanding that neither the editorial board nor the SAVA or its office bearers accept any liability whatsoever with regard to any statement, fact, advertisement or recommendation made in this magazine. VetNews is published by the South African Veterinary Association STREET ADDRESS 47 Gemsbok Avenue, Monument Park, Pretoria, 0181, South Africa POSTAL ADDRESS P O Box 25033, Monument Park Pretoria, 0105, South Africa TELEPHONE +27 (0)12 346-1150 FAX General: +27 (0) 86 683 1839 Accounts: +27 (0) 86 509 2015 WEB www.sava.co.za CHANGE OF ADDRESS Please notify the SAVA by email: debbie@sava.co.za or letter: SAVA, P O Box 25033, Monument Park, Pretoria, 0105, South Africa CLASSIFIED ADVERTISEMENTS (Text to a maximum of 80 words) Sonja van Rooyen assistant@sava.co.za +27 (0)12 346 1150 DISPLAY ADVERTISEMENTS Sonja van Rooyen assistant@sava.co.za +27 (0)12 346 1150 DESIGN AND LAYOUT Sonja van Rooyen PRINTED BY Business Print: +27 (0)12 843 7638 VET nuus•news Diary / Dagboek II Dagboek • Diary Regulars / Gereeld 2 From the President 4 Editor’s notes / Redakteurs notas Articles / Artikels 6 Clostridial Enterotoxicosis in Dogs 10 Animals have no nationalities 16 Allogeneic Mesenchymal Stem Cells Association / Vereniging 26 CVC News 28 SAVA News 36 Legal Mews Events / Gebeure 18 World Veterinary Association Congress 2024 22 International Veterinary Officers Coalition (IVOC) Meeting 2024 32 Onderstepoort residence centenary celebrations Vet's Health / Gesondheid 38 Life Coaching Technical / Tegnies 39 Dental Column Relax / Ontspan 48 Life Plus 25 Marketplace / Markplein 42 Marketplace Jobs / Poste 43 Marketplace/Jobs / Poste 46 Classifieds / Snuffeladvertensies 12 26 22 Scan the QR code for easy access to this month's CPD article «

Vetnews | Mei 2024 2 « BACK TO CONTENTS “Animal care professionals are some of the most pain-saturated people I have ever worked with. The very thing that makes them great at their work, their empathy and dedication and love of animals, makes them vulnerable” – Psychotherapist J. Eric Gentry KNOW YOURSELF – WE NEED YOUR SUPPORT The World Veterinary Association Congress, in Cape Town has come and gone. Reports received is that it was a major success with participants enjoying the quality and variety of topics presented. Various reports will be made about the congress, but I want to dwell on the opening and closing sessions. The official welcoming was by Minister Ivan Meyer, the Minister of Agriculture of the Western Cape Government. In his welcoming speech, he highlighted the importance of veterinary services in the Western Cape and announced that since last year the Western Cape officially celebrated a week for veterinary services, a week that has now formally been included in the department’s plans and budget for the future. May this example extend to all other provinces to highlight the importance of veterinary services in the economy of our beloved country. His welcoming speech was followed by some official business, after which the attendees were introduced to the harsh conditions of delivering veterinary services under conditions of war by Prof Nataliia Klietsova, a Professor in International Relations, and Dr Andrii Kietsov, inter alia a veterinarian in Sumy Ukraine on “Resilience of animals and doctors of veterinary medicine under conditions of war in frames of One Health”. What an emotional and shocking experience. After their presentation, a lot of time was spent with the couple to try and understand how they cope with the situation and what can be learned from them. I will get back to this. After their very emotional presentation, it was time for Prof Annemarie Hattingh, with more than 30 years of experience in professional development and learning, to address the delegates on “Have I signed up for this? Re-constructing my professional identity in the intersection of ideals and supercomplex, catastrophic realities”. She got off to a very emotional start as most of the delegates, herself included, still had to wipe and swallow the tears of the previous presentation. Her focus was on the removed reality of what you thought you were letting yourself into, and the stark reality of veterinary services and what you can do to try and cope. The final item of the closing ceremony was performed by Jedd DeGenerous, a beatboxer. Not only was his performance amazing, but he also shared his sad difficult story with the delegates. His whole family were addicts of a sort, but he found his solace in music. Music became his escape valve for all the stress. He could have so easily fallen into the trap of addiction. What was a common golden thread through all these presentations, also reverberated later in some of the presentations, is that you need to know yourself to be able to learn how to cope with difficulties. We as veterinarians are so focused on our patients, clients and the service that we must render, that we forget about ourselves. Our good character traits are those that also make us vulnerable. After the congress, I was contacted by Dr Etienne van der Walt from Neurozone who surveyed SAVA last year about the mental wellbeing of our veterinarians. They, after listening and participating in the congress, took the results and further analysed them(The report will be published in VetNews) and concluded that our veterinarians are in dire straits, much worse than expected, and urgent intervention should be instilled. I want to appeal to all veterinarians to, if not already done, initiate a process to know yourself and to learn how to cope with stressors. SAVA is committed to the process of supporting our members through the development of the necessary tools and programs, but need your support. The veterinary community’s mental wellbeing should and must be a collective effort of all our members as we all play an extremely important intricate role in it. I, as President of SAVA, want to appeal to every member to support SAVA’s efforts to bring a change in the mental health profile of Veterinarians. Even if our efforts make a difference in only one member’s situation, preventing him/her from committing suicide, it will already be an extremely important accomplishment. v Kind regards, Paul van der Merwe From the President Dear members,

Vetnuus | May 2024 3 “The South African Veterinary Association aims to serve its members and to further the status and image of the veterinarian. We are committed to upholding the highest professional and scientific standards by utilising the professional knowledge, skill and resources of our members, to foster close ties with the community and thus promote the health and welfare of animals and mankind”. MISSION STATEMENT Servicing and enhancing the veterinary community since 1920! Tel: 012 346 1150 E-mail: vethouse@sava.co.za www.sava.co.za

Vetnews | Mei 2024 4 « BACK TO CONTENTS In a world where you can be anything, be kind To work with animals, you must be the kindest of all people. They cannot physically thank you and sometimes they may even try to attack even if your intentions are good and pure. The question is: How kind are you to yourself? Do you know that amongst all the pressures you are enough? Do you give yourself enough time to recover after a rough period? I hope you find a ‘safe’ space to let go of frustrations. It could be a hobby, exercise, or nature. Maybe it is friends’ company or being alone. It comes back to knowing yourself. Finding the thing that restores your beautiful soul. I hope that you can make that greatest discovery, the fact that here and now, YOU ARE ENOUGH! It was great to meet up with old and new friends in Cape Town. Vets are for sure a very special family. Thank you to every person who dropped in at the SAVA stand. Thank you to every person who made the congress the huge success it was. I got to attend a couple of sessions, some of which by very interesting presenters. Fortunately, the congress was not all work and no play. The congress was opened in great Cape Town style with a wine-tasting by Delheim, sponsored by Design Biologix, with some live music to add to the great atmosphere. Vetnews will have more on the congress next month. I hope that May brings peace, knowledge and kindness. Andriette v From the Editor Editor’s notes / Redakteurs notas

Vetnuus | May 2024 5 We, the members of the Association, resolve at all times: • To honour our profession and the Veterinary Oath • To maintain and uphold high professional and scientific standards • To use our professional knowledge, skills and resources to protect and promote the health and welfare of animals and humans • To further the status and image of the veterinarian and to foster and enrich veterinary science • To promote the interests of our Association and fellowship amongst its members. Ons, die lede van die Vereniging, onderneem om te alle tye: • Ons professie in ere te hou en die Eed na te kom • ‘n Hoë professionele en wetenskaplike peil te handhaaf en te onderhou • Ons professionele kennis, vaardigheid en hulpbronne aan te wend ter beskerming en bevordering van die gesondheid en welsyn van dier en mens • Die status en beeld van die veearts te bevorder en die veeartsenykunde te verryk • Die belange van ons Vereniging en die genootskap tussen sy lede te bevorder. CREDO

Vetnews | Mei 2024 6 « BACK TO CONTENTS Clostridial diseases are well known and described in veterinary medicine and include tetanus, botulism, gangrene, “black leg,” lamb dysentery and necrotic enteritis in poultry, to name a few. CLOSTRIDIA HAVE SEVERAL FEATURES: • They are gram-positive. • They produce toxins. • They are anaerobic (they grow in the absence of oxygen). • They form spores (essentially armour) to withstand environmental change, including disinfectants that would kill more vulnerable bacteria. • Five biotypes (A, B, C, D and E) depending on what combination of four toxins it produces. • Dogs are almost exclusively infected with biotype A. This bacterium is often present in the intestine asymptomatically, and only when it starts to proliferate, will it produce spores and toxins. Causes for proliferation include stressors such as a diet change, allergic reactions, environmental disturbances such as staying in a hospital or a kennel. This overgrowth leads to production of spores and toxins which have severe e ects on the enterocytes (cells lining the gastrointestinal tract). TYPES OF DIARRHOEA: Acute – Self-limiting symptoms of diarrhoea lasting 5-7 days. Chronic – Recurrent symptoms occurring every 4-6 weeks (more common in older dogs). Haemorrhagic gastroenteritis – Sudden symptoms of profuse bloody diarrhoea and vomiting. Clostridium perfringens produce more than 16 toxins, of which Alpha, Epsilon, net E & net F are the ones involved in canines. In order to produce these toxins, sporulation must happen. The organism may have been innocuously living in the intestine for some time when something causes it to sporulate and produce toxins. These toxins ulcerate the intestinal lining, and the intestinal blood vessels become permeable, this leads to fluid being lost into the intestinal lumen, causing dehydration, an elevated haematocrit (red blood cells in relation to serum), and bleeding ulcers. CLOSTRIDIAL ENTEROTOXICOSIS IN DOGS Written by Dr. Elizna Boag.

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Vetnews | Mei 2024 8 « BACK TO CONTENTS Some dogs tend to get recurrent bouts of haemorrhagic gastroenteritis, and preventing such episodes is managed by feeding diets which promote a healthy gastrointestinal microbiome. Montego’s Karoo Targeted Care range o ers the Sensitive Gut Health diet for dogs with sensitive gastrointestinal systems. KAROO TARGETED CARE SENSITIVE GUT HEALTH DIET DIGESTIVE SUPPORT FOR AND OVERALL GUT CONDITIONING Karoo’s Sensitive Gut Health diet for adult dogs is made with a single-grain recipe with turkey, lamb, and brown rice. It provides digestive support for adult dogs with digestive sensitivities causing indigestion, constipation, or diarrhoea. Therefore, to support the aim of this diet, ingredients were selected to form an ideal blend for high digestibility, digestive support, and overall gut conditioning. The duo-protein in this product is turkey and lamb, and the ingredients that speci cally target gut health include whole egg powder, zeolite, milk thistle, bromelain, prebiotics which include inulin and beet pulp, and a probiotic.

Vetnuus | May 2024 9 Bacillus subtilis Bacillus subtilis Bacillus subtilis PB

Vetnews | Mei 2024 10 « BACK TO CONTENTS Animals have no nationalities The theme of the 39th World Veterinary Conference held in Cape Town in the middle of April 2024 was Resilience in the face of adversity. When looking at the world in 2024 it is not difficult to realise that the world is in great difficulty. The 39th World Veterinary Associations Congress in Cape Town was opened by one of the most soul-destroying presentations I have ever heard. I met with Prof Natalia Klietsova and Dr Andriy Klietsov over a cup of coffee to talk about being a veterinarian in a warstricken country. Andriy speaks fluent Russian, by mine is not so umh, not at all functional. Natalie speaks fluent English, not only with the words but with the passion to match. Please find links to some very disturbing footage at the end of this article. But be warned, it is not for the faint of heart I jumped right in and asked Andriy about the conditions in his country. Andriy looks out the window as if to find the words from outside. “It is very bad. Before the invasion, there were lots of talk. We still went to visit family in Russia a couple of days before it happened. The guards at the border post seemed very nervous about when we were returning. We just laughed. We had a great time celebrating my grandmother’s birthday. Our town Sumy is in the Sumy Oblast province, it borders directly on Russia. One morning we woke up with Russian tanks in our city. The bombing started, and there was no air protection for us. We all ran into bomb shelters. But the animals were still out there. Lots of animals in shelters throughout the city. They had nowhere to go. The people tried to take care of them. The Caretakers took as many as they could into their own bomb shelters. We were quickly cut off from the outside. The people started panicking and went into shops to buy everything they could. We tried to help by not allowing one person to take everything so that the available supplies could last for everyone. Human food and animal food became very scarce. A lot of people died. The air raid sirens sounded night and day. The people of Sumy are very brave. They pushed the invaders out of the city. We had no weapons but we fought them out. The city was completely sealed off. Later on, there were “Green Corridors” but it was never safe, the Invaders did not stick to any arrangement and bombing took place at any time. No human food was allowed in. We took a large grain truck from a farmer and excited the city to collect food for the animals. We were checked and sometimes returned empty to show that we did not want to make trouble. Sometimes we could hide human supplies under the animal food. The truck was very deep and difficult to see all that was in there. We helped a lot of people like this. We struggle with all supplies, even if it can be donated, it is difficult to get in safely. I often drive my car and fetch as much as I can fit in and distribute it to the animals in need. Many Veterinarian hospitals are totally destroyed. I had students who helped in the clinic, but they were too scared to drive there, they would phone and I would go and pick them up. It is dangerous for humans and animals. The reality of being a Veterinarian in a War zone When two elephants fight, it is the grass that gets trampled – African Proverb

Vetnuus | May 2024 11 Poland opened the borders for refugees and a lot of people took their animals with them. But it was not easy as the border needed the animals to be vaccinated and identified. We did what we could with the supplies we had. We still vaccinate, sterilize and identity chip a lot of animals. Some people who could not take their animals left them at the clinic pleading with us to look after them until they could return. There are so many destroyed houses, that I do not know what will happen to all the animals in the long run. Our colleagues in Poland helped us with a mobile clinic. Now we can get to the animals that cannot get to us. It makes the sterilizations a lot easier. We have a great shortage of personnel. Before the war, there were 25 people on the staff. Now we are only 3. Before we moved the children to a safer country they helped with some of the operations. Article >>> 12

Vetnews | Mei 2024 12 « BACK TO CONTENTS We try to treat all the animals that come in. Sometimes they are injured from the shrapnel or glass or metal after the bomb blasts. Lately, the mines have become a huge problem. Large parts of the countryside have been laid with anti-personnel and anti-vehicle mines. This is going to become a bigger and bigger problem. The farmland is being destroyed and the farmers are too scared to work the land. Sterilizations People love their dogs and lots of people try to help and adopt. Even some soldiers. Dogs forgive eveything. Feeding the animals I ask Andriy why he has not also left the country. His answer is simple. “If I leave, who will look after the animals? Who will help rebuild the country? I have hope that the War will be over and we will be able to rebuild. It is difficult with my family being away so far but I get to see them and I get to travel the world and tell the truth. There is a lot of lies. Many, many people still think the war is a lie, and that the photos Animals have no nationalities <<< 11

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Vetnews | Mei 2024 14 « BACK TO CONTENTS and footage are staged. We have to tell the truth of what is happening to the animals. But it is not only domestic dogs and cats. Many farm animals have been destroyed and even animals in the zoo. We, who are here must help stop that from happening again. Veterinarians are the bridge builders. We look beyond nationalities and just help. He believes that with good deeds and actions, the world will be able to see what the facts are. There were 33 veterinarians killed in the war, this highlights the dedication of the people in our profession. We do give up. There will always be animals to help, no matter where in the world you go. What makes you resilient?“You never know how strong you can be, until strong is all you have left”But you have to know yourself, you must know when you are at breaking point, and then you must rest, you must remove yourself from that situation and restore. In both these quotes, the ability is very prominent. It points back to the person to handle the stress, misfortune, or change. You will never know what tomorrow will bring. Maybe the enemy will withdraw or maybe some bombs will fall. You cannot wait for the day to arrive and not have a plan for it. Make your plans, but also be ready that something can happen that can change the best plans you have into something even better or cancel the plans. Do not lose heart if everything does not happen the exact way you planned. Very often the new route is much better than the one you envisage. Draw energy from your successes and remember you may not be able to help all the animals but you can the ones that are presented to you. Learn from your mistakes, it will make you better, stronger and wiser. But do not stay disheartened by them, make your stay there temporary, rather make your successes your permanent dwelling. “Some patients come into your life as blessings, others as lessons” May the veterinarians worldwide stand together, stay neutral, and protect the most vulnerable grass from being trampled. v Everyday Health says: “Resilience is the ability to withstand adversity and bounce back from difficult life events. Being resilient does not mean you never experience stress, emotional upheaval, and suffering. Resilience involves the ability to work through emotional pain and suffering.” Do not allow yourselves to be disheartened by any failure as long as you have done your best. – Mother Teresa WVAC Opening presentation link: https://prezi.com/ view/3zEcscpDiNLkqnpCujZt/ This video is very very graphic, please open with care, it is not for the faint of heart: https://www.youtube.com/wa tch?app=desktop&v=piwIrvb YwW8&t=4s#bottom-sheet Article Animals have no nationalities <<< 13

Vetnuus | May 2024 15 MANAGING YOUR CPD COMPLIANCE We understand that managing your CPD requirements can be a time consuming and somewhat frustrating process, which is why we want to introduce you to VetEDonline. VetEDonline is an online CPD Management and Education Platform endorsed by the South African Veterinary Association (SAVA), which provide veterinarians with state of the art CPD Compliance and Education Solutions that assist them on their journey to CPD compliance. CONTINUING PROFESSIONAL DEVELOPMENT FOR VETERINARIANS As a registered veterinarian, you have a responsibility to improve your knowledge and skills on regular basis for the end benefit of your patients. This responsibility is the driving factor behind the Continuing Professional Development (CPD) programme implemented by the South African Veterinary Council (SAVC). VETEDONLINE SUPPORTS PRACTICING VETERINARIANS WITH THEIR CPD COMPLIANCE BY PROVIDING THE FOLLOWING SOLUTIONS AND SERVICES: WHAT IS CPD? CPD is a process of lifelong learning whereby a Veterinary or Para-Veterinary Professional systematically engages in activities that maintain abilities, skills and knowledge required for a professional practice. HOW DOES CPD WORK? According to the SAVC’s guidelines, veterinarians who enter the CPD system during their Compulsive Community Service, must accumulate a minimum total of sixty (60) CPD points, of which twenty (20) points must be Structured CPD, within every three-year cycle from commencement of the CPD system. Visit our VetEDonline Platform for a detailed breakdown of your Structured and Unstructured CPD requirements. As a practicing veterinarian, the SAVC advises that you continuously accumulate your CPD points as part of your professional development portfolio which starts during your community service year. It remains the responsibility of veterinarians to keep record and documented proof the of their CPD activities. A summary of all activities is to be submitted on an annual basis to the council on a form that is obtainable from the registrar. ONLINE LEARNING PORTFOLIO To manage your CPD certificates and keep track of your CPD points ONLINE COURSES Online Courses from leading providers JOURNALS & ARTICLES CPD accredited articles from SAVA What to expect as a practising veterinarian regarding your CPD requirements as set out by the SAVC? Contact us for more information and guidance on your CPD compliance +27 12 111 7000 | support@veted.online | www.veted.online

Vetnews | Mei 2024 16 « BACK TO CONTENTS Allogeneic Mesenchymal Stem Cells: a step into the future for patients with degenerative osteoarthritis Marianne Lomberg BVSc Hons With improvements in health care and nutrition, our companion animals are living longer. Unfortunately, that also means degenerative conditions such as osteoarthritis are being diagnosed at an increasing rate in dogs, cats and horses. When inflammation goes bad: the molecular basis of degenerative osteoarthritis Degenerative joint disease is a physiological condition as much as a mechanical one. Macroscopically, it is the wearing away of intraarticular cartilage at a rate higher than the body’s ability to repair it. Physiologically, though, the process is more complex. The breakdown of cells causes the release of pro-inflammatory cytokines and other catabolic mediators in the joint. The purpose: to attract cells which can clean up the damaged tissue, revascularise and build new tissue to replace it. In a discrete, acute injury, this works perfectly. However, in animals with chronically unstable joints, the ongoing damage occurs faster than the body can repair it. The result is an ongoing inflammatory cytokine response which causes a continuous catabolic state and with it, chronic pain. (Sutton et al, 2009) Rebalancing the inflammatory response Interventions for degenerative osteoarthritis are aimed at either reducing the speed of breakdown or increasing the speed of regeneration, to the point where balance is restored. This can be done in four ways: 1) Reducing the inflammatory response through medication or dietary anti-inflammatory supplementation slows the catabolic process. However, in highly catabolic states or very unstable, far-progressed joints, these alone are insufficient to ensure the return to quality of life for patients. 2) Reducing mechanical pressure on the affected joints through surgery, weight management or exercises aimed at strengthening the surrounding muscles. This reduces the cause of joint wear, but it doesn’t correct the molecular process and therefore may not be sufficient for returning quality of life. 3) Placing an inert barrier between the nerve-containing tissues in affected joints. Intra-articular installations of viscoprosthetic agents such as polyacrylamide (Noltrex™, distributed in SA by V-Tech), provide this mechanical pain relief and can be life-saving in patients where owner finances or patient age do not allow corrective interventions, but the fact that a viscous, infiltrative foreign body is being permanently placed in a joint reduces its desirability in younger animals. 4) Encouraging tissue repair. In the past, this was achieved by placing the building blocks of the damaged cells into the body and relying on existing cells to use them appropriately – think dietary glucosamine supplementation or hyaluronic acid injections - or by focusing the body’s repair response on the damaged tissue – the principle used in Platelet Rich Plasma treatments. Recently, veterinarians have been able to add stem cell therapy to the regenerative modalities used. What makes stem cells different from other regenerative modalities? In fact, every treatment modality aimed at increasing the rate of tissue repair relies on stem cells. • In Platelet Rich Plasma (PRP) administration, the aim is to degranulate platelets before administration. This causes the release of chemotactic agents which attract leukocytes (to clear up the damaged tissue fragments) and haematopoietic progenitor cells – stem cells primed to become blood vessels. So PRP is essentially a way of directing the body’s stem cells towards treated areas. • Autologous Stromal Vascular Fraction (SVF) administration, goes one step further. When using this method, practitioners harvest mesenchymal fat. The fat is prepared with the aim of isolating and concentrating the stem cells. SVF administration delivers stem cells directly to the area where they’re needed. However, preparation is costly and time-consuming, and it is impossible to verify how many viable stem cells are being administered. • This is why Allogeneic Mesenchymal Stem Cells have become the most desirable tool for enhancing the physiological process of tissue regeneration. After harvesting visceral fat, the cells are not simply isolated and concentrated as with SVF, but then cultured (encouraged to multiply). In the process, Major Histocompatibility Complex (MHC) type II surface markers which identify cells as originating from a different host animal, are also removed. This means that stem cells from one donor can be used in a different patient – making allogeneic mesenchymal stem cells (MSCs) an off-the-shelf solution.

Vetnuus | May 2024 17 The benefits of allogeneic MSCs over autologous Stromal Vascular Fraction 1. Reliable quantities of stem cells in every ml 2. Guarantee that the cells being administered are viable stem cells: flow cytometry carried out on every batch tests for the absence of leukocytes and the presence of the markers of viable stem cells. 3. Absence of MHC markers that would identify cells as originating from a different host 4. Ease of preparation since the cells arrive ready for administration. 5. Significantly lower cost than for SVF – less than half the cost in most markets and most animals. While PRP treatment needs to be administered every 6 months to retain its effect, a single administration of allogeneic stem cells has been shown to have a duration of effect of significantly over 2 years – up to 5 years in some studies, yet the cost is generally lower than a year of treatment with PRP (Alves 2021, Kriston-Pál 2020) Taking the step into the future: what to know before applying allogeneic MSCs for the first time Allogeneic MSCs are contraindicated in patients with active infections, and not recommended for patients with a history of neoplasia, but may become a valuable new tool to enhance quality of life for our patients. References Sutton S, Clutterbuck A, Harris P, Gent T, Freeman S, Foster N, et al. The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis Vet J. 2009;179(1):10–24. Alves, J.C., Santos, A. & Jorge, P. Platelet-rich plasma therapy in dogs with bilateral hip osteoarthritis. BMC Vet Res 17, 207 (2021). https://doi.org/10.1186/s12917-021-02913-x Kriston-Pál É, Haracska L, Cooper P, Kiss-Tóth E, Szukacsov V, Monostori É. A Regenerative Approach to Canine Osteoarthritis Using Allogeneic, Adipose-Derived Mesenchymal Stem Cells. Safety Results of a LongTerm Follow-Up. Front Vet Sci. 2020 Aug 13;7:510. doi: 10.3389/ fvets.2020.00510. PMID: 32903517; PMCID: PMC7438407. Conflict of interest statement: The author is a shareholder in a company that manufactures allogeneic MSCs for veterinary use. This article was sponsored by V-Tech, the agent that supplies VetRenew stem cells (www.vetrenew.co.za) in Southern Africa. For more information or product support contact your local V-Tech representative or Customer Care on +27 87 250 5925 / info@v-tech.com. v We compound veterinary medicines www.v-tech.co.za / Tel: +27 87 150 5925 (SA) Figure 1: an example of a flow cytometry batch analysis on allogeneic stem cells. CD29 and CD90 surface markers indicate the presence of viable stem cells, absence of CD34 and CD45 markers indicates the absence of angiogenitor- and white blood cells. Article

Vetnews | Mei 2024 18 « BACK TO CONTENTS “Resilience in the face of adversity” - a theme that encapsulates not only the spirit of the 39th World Veterinary Association Congress (WVAC2024) but also the enduring legacy of this esteemed gathering. Since its inception in 1863, the WVA Congress has weathered the storms of history, including two world wars, two pandemics, and numerous global crises. In selecting this theme, the organizers aptly recognized the ongoing challenges facing the veterinary profession and the need to cultivate resilience among its practitioners. From April 16th to 19th, 2024, Cape Town played host to a momentous convergence of veterinary professionals from across the globe. With meticulous planning initiated since the bid process in 2021, the Congress burgeoned into an unparalleled assembly, drawing over 1650 attendees from more than 48 countries. We were also honoured to host delegations from the WOAH, FAO, UNEP, OHHLELP, WSAVA, IVSA and the WFO. This diverse and dynamic gathering underscored the international reach and significance of the veterinary community. The Congress unfolded as a vibrant tapestry of knowledge exchange, innovation, and collaboration. Over four days, attendees were immersed in a rich array of presentations, workshops, and discussions encompassing the breadth of veterinary science. From cutting-edge research to clinical best practices, the program offered a wealth of inspiration and insight to propel professional journeys forward. Amidst the festivities, the Congress remained grounded in its commitment to addressing pressing global challenges. The opening address by the Minister of Agriculture in the Western Cape, Minister Ivan Meyer, underscored the pivotal role of veterinary medicine in safeguarding animal and public health, as well as environmental sustainability. The Minister’s advocacy for the One Health Strategy highlighted the interconnectedness of human, animal, and environmental well-being, emphasizing the need for collaborative approaches to address complex health issues. The Congress boasted a vibrant atmosphere with 70 exhibitors showcasing cutting-edge technologies, innovative products, and services shaping the future of veterinary medicine. Moreover, it served as a platform for intellectual exchange, hosting over 270 speakers who delivered a staggering 433 presentations over four days. One of the hallmark features of the Congress was its inclusivity, evident through the comprehensive array of specialized conferences catering to diverse interests within the veterinary field. From the South African Veterinary Association (SAVA), the National Veterinary Clinicians Group, the Ruminant Veterinary Association of South Africa, the South African Equine Veterinary Association, the Veterinary Exploring the Pinnacle of Veterinary Science: Highlights from the 39th World Veterinary Association Congress Events I WVAC 2024

Vetnuus | May 2024 19 Nurses Association of South Africa, the Veterinary History Society of South Africa, all the Veterinary and Para-veterinary Professions, Health and Animal Welfare Societies, the Congress offered a tailored experience for attendees representing various sectors of the industry underscored the Congress’s commitment to addressing the multifaceted dimensions of veterinary practice. The stellar lineup of speakers further enriched the Congress experience, with luminaries and thought leaders from around the world offering unique perspectives and expertise. Keynote sessions delved into topics of global significance, including resilience in the context of conflict, with insights shared by distinguished speakers from Ukraine. Some of the highlights to mention include the: • 10th WVA Global One Health Summit • The WVA Global Veterinary Awards • The Welcome Reception introduces wine farms from across the Cape • The dazzling congress dinner at GOLD Restaurant We would also like to take this opportunity to thank our organising committees for their dedication, and selfless commitment: • Dr Paul van der Merwe, Congress Chairperson SAVA • Dr Charlotte Nkuna, Congress Co-Chairperson • Dr Rafael Laguens, WVA President 2022-2024 • Dr John de Jong, WVA President-Elect 2024-2026 • Mr Gert Steyn, Operational Director SAVA • Dr Tom Spencer, Financial Director SAVA • Prof. Adrian Tordiffe, Programme Chairperson • Ms Magda Lourenço, WVA Executive Manager • Ms Yvonne Niño, WVA Policy Officer Our Scientific Programme Committee: • Dr Adrian Tordiffe, Scientific Programme Chairperson • Prof. Gareth Bath • Dr Geoff Brown • Dr Janine Burger • Dr Richard Burroughs • Dr Liesl de Boni • Dr Kurt de Cramer • Dr Jordi Franch • Dr Andy Fraser • Sr Cornelia Hanekom • Prof. Kenneth Joubert • Dr Liesel Laubscher • Sr Reinette Ludike • Prof. Ivan Lwanga-Iga • Dr Sean Miller • Dr Dave Miller • Dr Greg Simpson • Dr Chris van Dijk And last but not least, our congress organisers from SAVETCON Event Management: • Ms Corné Engelbrecht • Mrs Melanie Pretorius • Ms Nthabiseng Letsoalo • Mrs Erika Kruger >>> 20 Events I WVAC 2024

Vetnews | Mei 2024 20 « BACK TO CONTENTS As the curtains closed on the 39th WVA Congress, it left an indelible mark on the veterinary community, reaffirming its role as a beacon of resilience, innovation, and collaboration. The success of this event would not have been possible without the dedication of our sponsors, partners, organizers, and the unwavering support of the veterinary profession worldwide as well as the veterinary profession of South Africa for the amazing support received and especially for the belief that we were capable of staging an event of this magnitude. Looking ahead, the legacy of the Congress serves as a guiding light, inspiring continued efforts to advance the noble profession of veterinary medicine and chart a course towards a healthier, more sustainable world for all living beings. In the face of adversity, we stand united, fortified by our shared commitment to excellence and our unwavering resolve to overcome challenges together . v Events I WVAC 2024

Vetnuus | May 2024 21 Events I WVAC 2024

Vetnews | Mei 2024 22 « BACK TO CONTENTS International Veterinary Officers Coalition (IVOC) Meeting 2024 – Cape Town AVA was represented by Dr Diana Barker, AVMA by Drs Rena Carlson, Beth Sabin, Lorri Teller and Pat Turner, BVA by Dr Malcolm Morley and Mr David Calpin, CVMA by Dr Trevor Lawson and Mr Joel Neumeier, NZVA by Dr Robert Mills and SAVA by Drs Paul vd Merwe, Ziyanda Majokweni and Mr Gert Steyn. The International Veterinary Officers Coalition (IVOC) consists of the Presidents and the CEOs of the following: the American Veterinary Medical Association (AVMA), the Canadian Veterinary Medical Association (CVMA), the British Veterinary Association (BVA), the South African Veterinary Association (SAVA), the Australian Veterinary Association (AVA), and the New Zeeland Veterinary Association (NZVA).

Vetnuus | May 2024 23 As part of cost savings measures the IVOC meeting and the World Veterinary Association Congress usually go hand in hand as all attendees are already involved in the World Veterinary Association Congress. Early on the 13th of April, the delegates got together for a long day of talks and discussions. First on the agenda were the Feedback reports of the different countries. Main issues that confronted the different Associations through the past year, and planned activities for the period until the next year were discussed. Common ground is sought and possible solutions are discussed and shared. By 16h00 the team was pretty ready for a break in discussions. After a quick meet and greet with the accompanying spouses, we left for the Silvermist estate for the first test of South African wines for the group. Not only was the group met by Warren and Tammy, our hosts, but also the adorable potbelly pig named Miley. The wine tasting was done by the winemaker himself: Greg Louw. He explained the farm was developed into an organic winery, how important his little red dog was to him and how he honoured his little friend on the label of his wines. He presented some very old and rare wines as well as new and exciting stock. All this was done under the watchful eye of the setting sun. Before dinner, the guests were invited into the world of African musical instruments by the music master himself and his Drumstruck group. Drumstruck is an exhilarating interactive drumming experience that transcends language and connects people through the universal language of rhythm. If the group was not connected by the common ground of veterinary science, they were definitely now connected by the rhythm of the drums. Under the amazing guidance of Mpho Rasenyalo the final layer of ice was broken. The IVOC group meetings are usually a somewhat formal group with functions quite formal. South Africa broke this wide open. Events I IVOC 2024

Vetnews | Mei 2024 24 « BACK TO CONTENTS Before the lunch break on 14th April, AVMA presented the planned next WVAC in 2025 in Washington DC. After lunch, the group was taken on a short sightseeing tour around the city. After freshening up and dressing for the occasion the group were welcomed at the prestigious Twelve Apostles Hotel by a breathtaking sunset, oysters and Sparking wine (read Champagne). What followed was one taste experience after the other with a 5-course meal and paired wine. The more formal event and setting did not dampen the spirits of the previous evening and before long some serious singing and dancing were happening. Events I IVOC 2024

Vetnuus | May 2024 25 IVOC meetings may look a little different in future but the value of sharing challenges, triumphs and tribulations over continents can never be underestimated. Strong bonds are formed, solutions shared. v For Vets, Vet Nurses and Practice Managers. Convenient Personalised Immediate. Introducing the first ever veterinary specific on-demand web and app-based recruitment platform. MEET YOUR MATCH WITH Go to www.guavavet.com to find out more! Events I IVOC 2024

Vetnews | Mei 2024 26 « BACK TO CONTENTS Kariega Foundation and Domestic Animal Care - Kenton on Sea together with Community Veterinary Services Southern Africa held another successful mass sterilisation outreach in Ekuphumleni sterilising 56 dogs. Last year October they also sterilised 54 dogs. With the township of Marselle now 97% sterilised they are focussed on Ekuphumleni and making steady progress. Domestic Animal Care - Kenton On Sea ( DAC) sterilises 24 community dogs plus cats every month at Kariega Community Veterinary Clinic- Kenton (KCVC). They also have all their sick and injured community dogs and cats attended to by the very compassionate and caring vets at KCVC. Domestic Animal Care - Kenton is not a registered NPO so all donations are paid directly to the KCVC account. DAC is a small group of volunteers that transport the dogs and cats to and from KCVC and try as best they can to see to the welfare needs of their community dogs and cats. The dogs are all vaccinated 5 in 1 and rabies when they are sterilised. Cats also receive rabies vaccinations. Mange, parvo virus and distemper are now seldom seen in these townships. Dr Marette Dreyer has done outreaches in Marselle to do rabies vaccinations and Vets Go Wild under the direction of Dr William Fowlds and Ikhala Veterinary Clinic hold at least 3 -4 outreaches yearly in the surrounding townships and Alexandria to give rabies vaccinations and deworm tablets. v An initiative of the SOUTH AFRICAN VETERINARY ASSOCIATION Non-profit Company: 1998/016654/08 Non-profit Organisation: 000-234 NPO Public Benefit Organisation: 130001321 CVC News I CVC Nuus Kariega Foundation and Domestic Animal Care: Mass Sterilisation Outreach written by Verona Veltman from Kariega Vet CVC

Vetnuus | May 2024 27 CVC News I CVC Nuus SAVA-CVC & EduCVC are registered on PayPal and PayFast! All donations qualify for an 18A Tax certificate which means your donation is tax deductible! Please contact us cvcmanager@sava.co.za for details. Bank details: Organization name: SAVA-CVC Company Registration No: 1998/016654/08 ABSA Bank Cheque Account: 4056779023 Branch: Brooklyn (632005) Swift Code: ABSA ZAJJ Organization name: EduCVC Company Registration No: 2019/570769/08 FNB Bank Cheque Account: 6283 6622 531 Branch: Brooklyn: 251345 SWIFT Code: FIRNZAJJ

Vetnews | Mei 2024 28 « BACK TO CONTENTS In 2017, SAVA revived the mission of SAVA-CVC – providing quality veterinary care in impoverished communities. SAVA provided an interest free loan which was paid back in full and through significant efforts of the team managed to achieve impressive milestones. More than 80 000 small animal sterilizations, 193 000 small animal vaccinations,27 000 small animal disease treatments 192 000 endo/ecto parasite prophylaxis were administered, to mention but a few achievements. SAVA-CVC aims to drive the reality that owning an animal comes with a financial responsibility. Even in impoverished communities, we require clients to contribute to the treatment of the animals – albeit a small amount. It intends to respond to the issue that animal welfare organisations are overwhelmed by animals that do not receive proper veterinary care. To this end, we currently have 39 SAVA-CVC clinics around South Africa. What classifies a community clinic as a SAVA-CVC clinic? Firstly, an application form is completed by a member of SAVA. The requirements are no more onerous than performing this service out of sheer goodwill. The veterinarian must pass a CVC site visit to obtain a CVC certificate from the South African Veterinary Council if the veterinarian performs sterilizations outside of their veterinary clinic e.g. in community halls or schools. Secondly, all services rendered by animal health professionals at such a site must be supervised by a veterinarian. Thirdly, and this is critical – all activities and services rendered must be recorded and submitted in monthly reports to SAVACVC (this is done through an on-line portal). The reason for this is that SAVA-CVC approaches local and international donors to supply medicines, consumables and funds – something that is only possible through providing proof that veterinary services are rendered and that donations ultimately end up in the area where it is needed. In turn, SAVA-CVC then distributes these donations to its clinics around the country. All CVC clinics registered for support with SAVA-CVC is expected to uphold the highest professional veterinary standards and SAVA actively supports the veterinarians with the process to register with the South African Veterinary Council. We are aware of concerns by private practitioners that SAVA-CVC is“undercutting”the prices and services of private practitioners. Clinics classified as SAVA-CVC’s are guided by SAVA-CVC to avoid servicing animals belonging to people that can afford regular veterinary services. This includes, inter alia requesting proof of low income (SASSA cards with appropriate identification), subtly confirming that the animal being assisted is, in fact, owned by the person presenting the animal, and visual cues – clothes, watches, vehicles used when delivering the animal to the clinic. SAVA-CVC has preciously little resources and want to make sure that, as far as is humanly possible, services are rendered to those that absolutely cannot afford it. SAVA encourages veterinarians to offer primary veterinary care to animals in lower-income communities and SAVA members are invited to take advantage of the CVC benefits on offer to support your efforts. For more information, please contact Claudia Cloete on cvcmanager@sava.co.za v Gert Steyn Claudia Cloete SAVA Managing Director SAVA-CVC: Director SUPPORT FOR SAVA COMMUNITY VETERINARY CLINICS (SAVA-CVC)

Vetnuus | May 2024 29 Nominations for the SAVA Awards are invited. These awards are conferred on persons who have made exceptional and significant contributions in the fields of Veterinary Science or the Veterinary Profession and they serve as a prestigious form of recognition of distinguished service. They require sufficient but concise justification for the nomination in the category selected, as outlined in the criteria listed for each category. The presentation of awards will be made at a suitable venue and occasion identified by SAVA and this usually occurs every second year to coincide with the Gala Dinner of the SAVA Biennial Congress. Please adhere to the nomination guidelines as set out below. 1. GOLD MEDAL OF THE SAVA Awarded to any person, in recognition of outstanding and sustained scientific achievement, with a major impact in the field of veterinary science in South Africa. The medal will only be awarded once to a particular person, and there will be one award per year. The award requires a very comprehensive curriculum vitae and motivation. 2. PRESIDENT’S AWARD Awarded to any veterinarian registered with the SAVC in recognition of outstanding service to and advancement of the veterinary profession in South Africa. The award will only be bestowed once on a particular person, and there will be one award per year. The award requires a very comprehensive curriculum vitae and motivation. . 3. BOSWELL AWARD Awarded to any member of the SAVA for eminent service rendered to the profession through the SAVA. The award may be bestowed upon more than one person in a particular year. 4. CLINICAL AWARD OF THE SAVA Awarded to any veterinarian or group of veterinarians who are registered with the SAVC and have excelled in applied veterinary practice. There is a limit of one award per clinical discipline per year. Past recipients become eligible for another award after a period of five years, for a different contribution. 5. RESEARCH AWARD OF THE SAVA Awarded to one or more veterinarians for a body of research related to Veterinary Science, and published in scientific journals, that has made an important contribution to a particular field of study. Recipients of this award may be eligible for nomination for new original research. Submission to the Awards Committee may be made by candidates themselves. 6. YOUNG VETERINARIAN OF THE YEAR AWARD Awarded to one veterinarian registered with the SAVC per year, younger than 35 years of age or who has not been registered for longer than 10 years and who has made a significant contribution to veterinary science in his / her work sphere. 7. SOGA MEDAL Awarded in recognition of exceptional community service rendered by a veterinarian registered with the SAVC or a veterinary student enrolled at a South African veterinary faculty. In addition to veterinary-related services, other forms of community service may be considered to support the nomination. 8. CITATION OF THE SAVA The SAVA may bestow a citation upon one or more persons, including nonveterinarians, in recognition of specific achievements and / or meritorious contributions to the veterinary profession or the SAVA. More than one citation may be bestowed per year. 9. HONORARY LIFE MEMBER Any SAVA member who has rendered long and outstanding service to the veterinary profession may be awarded Honorary Life Membership. Honorary Life Membership will not be granted to more than three people in one year. 10. HONORARY ASSOCIATE LIFE MEMBER Any person who is not a veterinarian and who has rendered outstanding service to veterinary science, or the veterinary profession may be awarded honorary associate life membership. Honorary Associate Life Membership will not be granted to more than three people in one year. All nominations must be supported by: • Submissions must be made on the official nomination form available from the SAVA office. • A brief motivation in terms of the conditions of the specific award, including the impact the work of the nominee has had. Evidence supporting the motivation, such as testimonials, may be included. • A full curriculum vitae of the nominee, including a list of publication(s) where applicable and all the contact details of the nominee. • Copy (ies) of the relevant publication(s) in the case of the Research Award. • It should be clearly understood that all SAVA Awards are conferred for contributions that have been made specifically in a South African context and not elsewhere. Please note that: • Any member of the SAVA may submit nominations, while others making nominations must include the support and signature of a SAVA member. Nominators are encouraged to channel their nominations via a SAVA Group or Branch. • Non-SAVA members may be nominated for all categories except the Boswell Award and Honorary Life Membership. • Unsuccessful nominations of previous years may, at the discretion of the Awards Committee, be held over for consideration in the following year. • Where the nominator and seconder have indicated their permission, award categories of nominations could be changed by the Awards Committee. • Members of the Awards Committee are permitted to propose or second candidates for awards, on condition that they recuse themselves when such nominations are discussed. The onus is on members to submit appropriate nominations by the due date. Failure to comply with the above will lead to disqualification of the nomination. All nominations, in electronic format, marked for the attention of Prof G Bath, Chairperson, Awards Committee of the SAVA, must reach the SAVA Secretary Elize Nicholas elize@sava.co.za by FRIDAY, THE 31ST JULY 2024 Nomination forms may be obtained from Vethouse or the SAVA website or contact Elize Nicholas 012-346 1150 / 072-274 5434 CALL FOR NOMINATIONS FOR SAVA AWARDS AND HONORARY MEMBERSHIP 2024 PLEASE NOTE THE 2023 AND 2024 AWARDS/GALA DINNER WILL BE HELD ON FRIDAY 15TH NOVEMBER 2024 IN PRETORIA (VENUE TO BE CONFIRMED)

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